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Extramedullary plasmacytoma: rare neoplasm of parotid gland
  1. Sehrish Abrar1,
  2. Nasir Ali2,
  3. Bilal Mazhar Qureshi3,
  4. Ahmed Nadeem Abbasi3
  1. 1Department of Oncology, Section of Radiation Oncology, Aga Khan University Hospital, Karachi, Pakistan
  2. 2Radiation Oncology, Aga Khan University Hospital, Karachi, Sindh, Pakistan
  3. 3Department of Oncology, Aga Khan University, Karachi, Sindh, Pakistan
  1. Correspondence to Dr Sehrish Abrar, sehrishadeel499{at}


A 45-year-old man presented with left-sided facial swelling. Initial excisional biopsy was done somewhere else without prior imaging and it came out to be pleomorphic adenoma; local imaging after biopsy showed mass over the left parotid gland with ipsilateral lymphadenopathy. On examination, there was a well-circumscribed mass with signs of left facial nerve palsy. He underwent left radical parotidectomy with ipsilateral modified radical neck dissection, and per operatively, it came out to be neoplastic lesion. Final histopathology was plasma cell neoplasm of the parotid gland. After surgery, the patient received radiation therapy to the left parotid region on account of uncertain surgical margins. It has been 3 years down the road that there is no evidence of local recurrence or transformation into multiple myeloma. Available evidence reveals that mere surgery for extramedullary plasmacytoma is not enough for local control whenever there is doubt of residual disease consider radiation therapy.

  • oncology
  • radiotherapy

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  • Contributors NA is primary radiation oncologist of this patient and he took this case in MDT for concensus decision. ANA and BMQ assisted in major planning of radiotherapy in PEER REVIEW meeting. SA had the idea to report this case. SA and BMQ have played a major role in writing this case report. All the authors made a significant contribution to this study.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.