Cryptococcal meningitis is a life-threatening condition most commonly observed in immunocompromised individuals. We describe a daily cannabis smoker without evidence of immunodeficiency presenting with confirmed Cryptococcus neoformans meningitis. An investigation of cannabis samples from the patient’s preferred dispensary demonstrated contamination with several varieties of Cryptococcus, including C. neoformans, and other opportunistic fungi. These findings raise concern regarding the safety of dispensary-grade cannabis, even in immunocompetent users.
- healthcare improvement and patient safety
- infectious diseases
- disease and health outcomes
- drugs misuse (including addiction)
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Contributors Study concept and design: WWI, RH, BS, Danovitch I. Acquisition of data: RH, BS, BV. Analysis and interpretation of data: BS, Morgan M, Becker C, Nguyen C, Underhill DM. Drafting of the manuscript: BS, Kopple JD, BV. Critical revision of the manuscript for important intellectual content: BS, Kopple JD. Administrative, technical or material support: WWI, Danovitch I, BS. Study supervision: WWI, Danovitch I.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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