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Colonic perforation by an intrathecal baclofen pump catheter causing delayed Escherichia coli meningitis
  1. Oliver Patrick Devine1,
  2. Andrew Christopher Harborne2,
  3. William B Lo2,
  4. Rupert Price3
  1. 1 University College London Medical School, London, UK
  2. 2 Queen Elizabeth Hospital Birmingham, Birmingham, UK
  3. 3 Royal Stoke University Hospital, Stoke-on-Trent, Staffordshire, UK
  1. Correspondence to Mr Oliver Patrick Devine, oliver.devine{at}


Intrathecal baclofen (ITB) delivery via an implanted pump is frequently used for the treatment of spasticity. This is an effective and safe neurosurgical and pharmacological intervention associated with an improvement in patient quality of life. There is, however, a risk of device-related infection. We present a patient with pump-site infection and Escherichia coli meningitis secondary to transcolonic perforation of an intrathecal baclofen pump catheter. While this is rare, we review the intraoperative precautions and best practices that should be taken to prevent and manage this unusual complication.

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  • Contributors OD and ACH drafted the manuscript. WBL and RP critically revised the manuscript. All authors approved the final manuscript for publication.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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