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Intractable hyperemesis gravidarum in a patient with type 1 diabetes
  1. Muhammad Fahad Arshad1,
  2. Nasir Javed2,
  3. Mohammad Bekhit3
  1. 1Department of Diabetes and Endocrine, Doncaster Royal Infirmary, Doncaster, UK
  2. 2Department of Gastroenterology, Doncaster Royal Infirmary, Doncaster, UK
  3. 3Obstetrics and Gynaecology, Doncaster Royal Infirmary, Doncaster, UK
  1. Correspondence to Dr Muhammad Fahad Arshad, dr.fahadarshad{at}


Hyperemesis gravidarum is not uncommon. Its pathogenies is multifactorial but not fully understood. We present a case of a middle class, Caucasian pregnant woman aged 24 years with coexisting type 1 diabetes, who had severe hyperemesis gravidarum from the sixth week of pregnancy and was resistant to all standard and off-the-label treatments raising questions about the pathogenesis of hyperemesis gravidarum. She was managed with a multidisciplinary approach and was supported with total parenteral nutrition till she had an emergency caesarean section in the 29th week of pregnancy. Her vomiting stopped as soon as a small for gestational age but otherwise healthy male baby was delivered.

  • pregnancy
  • diabetes

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  • Contributors Conception and planning: MFA, MB. Literature search: NJ, MFA. Writing the report: MFA, NJ, MB.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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