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Solid pseudopapillary tumour (Frantz’s tumour) of the pancreas in childhood: successful management of late liver metastases with sunitinib and chemoembolisation
  1. Mauricio Antonio Escobar Jr1,
  2. John Mason McClellan2,
  3. William Thomas3
  1. 1Mary Bridge Children’s Hospital and Health Center, Pediatric Surgical Services, Tacoma, Washington, USA
  2. 2Department of General Surgery, Madigan Army Medical Center, Tacoma, Washington, USA
  3. 3Mary Bridge Children’s Hospital and Health Center, Tacoma, Washington, USA
  1. Correspondence to Dr Mauricio Antonio Escobar Jr, mauricio.escobar{at}


The patient is a girl aged 17 years who originally presented at age 11 years with a solid pseudopapillary tumour (SPT) in the head of the pancreas treated by an R0 pylorus-preserving Whipple procedure. The patient underwent surveillance CT every 3 months for the first year followed by MRI every 6 months. She was noted to have a new liver lesion in Couinaud segment VI highly suspicious for metastasis at 30 months. Liver wedge biopsy confirmed metastatic SPT. Two months later two new lesions were noted in Couinaud segment VII. The family preferred medical management to surgery resulting in a treatment combination of the tyrosine kinase inhibitor sunitinib and hepatic artery embolisation. The patient developed a hepatic abscess following embolisation but recovered with antibiotics. The patient has subsequently been followed with serial MRIs every 3 months, and 20 months following chemoembolisation, she has no evidence of recurrence of the metastases.

  • cancer intervention
  • chemotherapy
  • paediatric oncology
  • pancreatic cancer
  • paediatric surgery

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  • Contributors MAE and JMM contributed equally to this paper. Each of the authors attest to the following contribution statement. MAE, JMM, WT made substantial contributions to the conception and design of the work, the acquisition, analysis and interpretation of data and drafting the work. MAE and JMM revised the work critically for important intellectual content. MAE, JMM, WT provided final approval of the version published. MAE, JMM, WT agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Competing interests None declared.

  • Patient consent Parental/guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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