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Peripheral arterial disease as seen on X-ray and arteriography
  1. Antonio Lumbera Faltado Jr1,
  2. Mark Anthony Santiago Sandoval1,
  3. Leoncio Kaw2
  1. 1Section of Endocrinology, Diabetes and Metabolism, Department of Medicine, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines
  2. 2Section of Thoracic and Cardiovascular Surgery, Department of Surgery, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines
  1. Correspondence to Dr Antonio Lumbera Faltado Jr, aj_tons{at}

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An 80-year-old woman was admitted for a 2months history of non-healing ulcers on both feet. She is known to have type 2 diabetes, dyslipidaemia and hypertension for 30 years. She has a history of a femoral fracture on the left incurred after a fall 2 years ago for which she underwent open reduction and internal fixation.

On physical examination, there were ulcers on the lateral aspect of both feet and on the right malleolar area. Dorsalis pedis pulses were absent bilaterally.

An X-ray of both femurs was requested to check if the fracture healed properly and to rule out a new fracture since the patient remained bedridden despite surgery to correct the fracture. The X-ray revealed a metal implant on the left femur and with no new fracture. Incidentally, the femoral arteries were noted to be calcified along their entire length indicative of atherosclerosis (figure 1).

Figure 1

Lower extremity X-ray: calcified common femoral arteries (green arrows), deep femoral arteries (blue arrows) and superficial femoral arteries (red arrows).

Aortography with bilateral lower extremity run-off was done to demonstrate patency of the arteries. This showed heavily calcified but patent common femoral, profunda femoris, superficial femoral and popliteal arteries bilaterally (figure 2). Other pertinent findings were severely diseased and occluded anterior and posterior tibial arteries bilaterally. Both peroneal arteries were diseased but patent down to the distal leg.

Figure 2

Bilateral lower extremity aortogram: common femoral arteries (green arrows), deep femoral arteries (blue arrows) and superficial femoral arteries (red arrows). CIA; Common Internal Iliac Artery, EIA; External Iliac Arteries, IIA ; Internal Iliac Arteries

The patient was managed medically with statin, aspirin, diabetes and antihypertensive medications. Local wound care was also provided.

Vascular calcification increases with age particularly in patients with hypertension, dyslipidaemia, chronic kidney disease and diabetes. From age 20 to 90 years, the incidence increases by 30%.1 Moreover, the presence of heavily calcified vessels as measured by calcium scoring using CT may be correlated with disease severity and outcomes such as coronary artery disease, amputations and all-cause mortality among patients with peripheral arterial disease (PAD).2

Although catheter angiography is considered the reference standard in the diagnosis of PAD, an easily available and non-invasive modality such as Doppler ultrasound that does not require the use of potentially nephrotoxic contrast agents can also be used.1 Calcification of peripheral vessels may cause a decrease in elastic recoil of the involved vessel, leading to diminished Doppler signals (ie, from a triphasic flow to a biphasic or monophasic flow pattern).3 4 Plain radiography on the other hand is a valuable but semiquantitative tool in the detection of vascular calcification.

Learning points

  • Atherosclerosis can symmetrically affect the arteries of the lower extremities.

  • On this X-ray, we have seen both femoral arteries to be heavily calcified along their entire length.

  • Even if the femoral arteries are heavily calcified on X-ray, they can still be found to be patent on arteriography.


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  • Contributors ALFJ wrote the initial manuscript. MASS and LK contributed to the writing of the final version of the manuscript. LK performed the arteriogram. All were involved in the care of this patient.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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