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Unusual association of diseases/symptoms
CASE REPORT
Acute hepatitis B virus infection and severe non-immune haemolytic anaemia: a rare relationship
  1. Inês Furtado1,
  2. Diana Valadares2,
  3. Filipe Gaio Nery2
  1. 1Internal Medicine Department, Centro Hospitalar do Porto, Porto, Portugal
  2. 2Department of Intensive Care, Centro Hospitalar do Porto, Porto, Portugal
  1. Correspondence to Dr Inês Furtado, inessilvafurtado{at}gmail.com

Summary

The clinical presentation of acute hepatitis B virus (HBV) infection is usually related to the onset of liver failure and damage. Anaemia may occur, but it is only rarely attributed to haemolysis. The authors report about the case of a 41-year-old woman with the diagnosis of acute HBV infection and coagulopathy (without encephalopathy) who developed non-immune haemolytic anaemia. Total recovery of the analytical liver profile, coagulopathy and anaemia was achieved through treatment targeting HBV.This case shows that, although rare, non-immune haemolytic anaemia may occur in association with acute HBV infection and that HBV suppression seems to lead to progressive anaemia resolution.

  • infectious diseases
  • hepatitis and other gi infections
  • hepatitis b
  • haematology (incl blood transfusion)

https://doi.org/10.1136/bcr-2017-221763

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    Footnotes

    • Contributors FGN and DV contributed to the conception or design of the work. IF was responsible for data collection, analysis and interpretation. IF drafted the initial version of the article which was critically revised by FGN and DV. FGN, DV and IF approved the final version of the article to be published.

    • Competing interests None declared.

    • Patient consent Obtained.

    • Provenance and peer review Not commissioned; externally peer reviewed.