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It is important to consider the very high dose of elemental magnesium
(Mg) in this case of severe livery injury due to Epsom salt intake (1).
Using information from the Epsom Salt Council that Epsom Salts is 10%
elemental Mg by weight, and that one pound of Epsom Salts = 32 Tbsp, I
calculate that 3 Tbsp. Epsom Salts would deliver 4,250 mg elemental Mg.
This amount of supplemental Mg is definitely exces...
This amount of supplemental Mg is definitely excessive for only one
day let alone as a daily dose for 15 days.
The adult male RDA for Mg is 420 mg/day, one tenth of the daily dose
given in this case study (2). It is amazing that drug withdrawal and
adequate hydration were enough for an uneventful recovery with
normalization of liver function test after 38 days, showing how safe oral
Mg supplementation can be. However, even though quite safe, such
excessive doses (> 1,000 mg Mg/day) of this essential nutrient should
1. Philips CA, Paramaguru R, Mahadevan P, et al. Severe liver injury due
to Epsom salt naturopathy. BMJ Case Rep 2017;2017 doi: 10.1136/bcr-2017-
221718 [published Online First: 2017/10/04]
2. Institute of Medicine. Dietary reference intakes for calcium,
phosphorus, magnesium, vitamin D, and fluoride. Washington, D.C.: National
Academy Press 1997.