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An infant with congenital rubella syndrome in developing India
  1. Ajit Singh1,
  2. Sharon Narula2,
  3. Hashir Kareem1,
  4. Tom Devasia1
  1. 1Department of Cardiology, Kasturba Medical College Manipal, Manipal, India
  2. 2Department of Medicine, Kasturba Medical College, Manipal, Manipal, India
  1. Correspondence to Dr Ajit Singh, ajitjsingh.mcops{at}


Congenital rubella syndrome (CRS), caused by rubella virus infection during pregnancy, remains a public health concern in developing countries. Three to five per cent of all suspected CRS cases in India have been proven to be a rubella infection. Only about 45%–60% of pregnant women and infants in India receive the rubella vaccination. We present a case of a preterm female infant who tested positive for the rubella virus. The baby was born with low birth weight and, on examination, showed pallor and hepatosplenomegaly. She was detected to have an ostium secundum atrial septal defect (ASD) and a large patent ductus arteriosus (PDA) on echocardiography. On ophthalmic examination, she was diagnosed with bilateral cataract. She was treated with diuretics, and she underwent surgical correction for PDA. With this case we intend to present the literature, clinical manifestations and management of CRS. We will also focus on prevention, vaccination and disease burden in India.

  • infections
  • global health
  • vaccination/immunisation
  • congenital disorders
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  • Contributors SN: case data collection and manuscript first draft preparation. AS: manuscript reviewing, literature survey and correction, prepared the final draft. HK: planning of case report, design, data interpretation, helped in literature data collection. TD: planning of case report, reviewed the manuscript at various stages, correction and interpretation of data.

  • Competing interests None declared.

  • Patient consent Guardian consent obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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