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A disclosed diagnosis for 24 year’s unknown illness
  1. Shogo Hanai1,
  2. Kazushi Kinjo2,
  3. Madoka Uezato1,
  4. Yasuharu Tokuda3
  1. 1 Department of Internal Medicine, Nakagami General Hospital, Okinawa, Japan
  2. 2 Internal Medicine, Nakagami General Hospital, Okinawa, Okinawa, Japan
  3. 3 Department of General Internal Medicine, Tsukuba University, Mito, Ibaraki, Japan
  1. Correspondence to Professor Yasuharu Tokuda, yasuharu.tokuda{at}


IgG4-related disease (IgG4-RD) is a newly described illness over the last several years. A 57-year-old man, who had been followed for chronic kidney disease (CKD), chronic pancreatitis and history of operated cholangitis, was admitted to our hospital for abdominal pain and worsening renal function. Serum levels of IgG and IgG4 were elevated. CT scan showed the characteristic findings of IgG4-related retroperitoneal fibrosis, pancreas and kidney disease. An endoscopic biopsy revealed the finding compatible with IgG4-RD. Steroid therapy led to the remission of his abdominal pain. Patients with CKD of unknown aetiology may have IgG4-RD.

  • Pancreatitis
  • Chronic Renal Failure
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  • Contributors SH, KK and MU: cared the patient. SH, KK and YT: wrote the draft of the manuscript. All authors: contributed to the writing of the final version.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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