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CASE REPORT
Unresectable squamous cell carcinoma of upper trachea with long-term survival after concurrent chemoradiotherapy
  1. Prahlad H Yathiraj,
  2. Sandeep Ail,
  3. Anshul Singh,
  4. Vidyasagar Mamidipudi
  1. Department of Radiotherapy and Oncology, Manipal University, Kasturba Medical College, Manipal, Karnataka, India
  1. Correspondence to Dr Prahlad H Yathiraj, hyprahlad{at}gmail.com

Summary

Upper tracheal malignancies are rare, and long-term survival is even rarer, especially among the unresectable malignancies. A 66-year-old chronic smoker was diagnosed as a locally advanced, non-metastatic squamous cell carcinoma of the upper trachea. Being unresectable, he was treated with six cycles of concurrent weekly cisplatin and three-dimensional conformal radiotherapy to a dose of 60 Gy in 30 fractions over 6 weeks. Follow-up imaging at 6 and 12 months revealed no disease. Our patient is presently 36 months post-treatment and is disease free without tracheal necrosis, fistula or radiation pneumonitis but developed hypothyroidism and is presently euthyroid. Concurrent chemoradiotherapy appears safe up to 3 years at least without any necrosis and is effective in controlling local disease. Meticulous planning obviates the need for higher technology like motion management techniques or intensity-modulated radiotherapy.

  • oncology
  • radiotherapy
  • lung cancer (oncology)

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Footnotes

  • Contributors Patient and treatment details collection: SA. Manuscript preparation: SA and PHY. Discussion and references: PHY and AS. Manuscript review: AS and VM.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.