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Persistent oromandibular dystonia and angioedema secondary to haloperidol
  1. Ruziana Masiran
  1. Department of Psychiatry, Universiti Putra Malaysia, Serdang, Selangor, Malaysia
  1. Correspondence to Dr Ruziana Masiran, ruziana78m{at}


We report a case in a young man who developed acute, persistent and painful tongue protrusion followed by swelling for more than 24 hours. He had relapse symptoms of schizophrenia and had recently received a single dose of parenteral haloperidol to manage his agitation. His record showed history of similar event and he has been taking atypical antipsychotic for maintenance. Mental state examination on admission revealed an agitated man with disorganised speech, restricted affect, auditory hallucination and persecutory delusion. His dystonia and oedema improved after 3 days. His mental status also recovered with the maintenance of low-potency antipsychotic and anticholinergic antiparkinsonian medications.

  • psychiatry (drugs and medicines)
  • drugs: psychiatry
  • schizophrenia

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  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.