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Isolated prostate cancer soft tissue recurrence 10 years after radical prostatectomy
  1. Munad Khan1,
  2. Adee-Jonathan Davidson2,
  3. Madeleine McKinley3,
  4. Joseph Ischia1
  1. 1Urology, Austin Health, Heidleberg, Victoria, Australia
  2. 2Austin Health, Melbourne, Australia
  3. 3Austin Health, Heidleberg, Victoria, Australia
  1. Correspondence to Dr Munad Khan, munad.khan{at}


In advanced disease, prostate cancer is well known to invade locally as well as metastasise to distant locations. Metastases occur commonly in lymph nodes and bone but have also been known to involve certain visceral organs, particularly the lungs. Involvement of soft tissue by metastases is far less common, particularly in the context of cancer recurrence. We present the case of a male aged 68 years who presented with a rising prostate-specific antigen (PSA) 10 years after radical prostatectomy (RP). The PSA increased despite salvage radiotherapy and was ultimately found to be caused by a PSA secreting prostate cancer soft tissue mass in the suprapubic region. Surgical resection of the mass caused a sharp decline in the PSA to negligible levels. This case highlights the need for ongoing surveillance post-RP and the potential for prostate cancer recurrence in the soft tissue that is refractory to routine salvage radiotherapy.

  • Prostate
  • Surgical oncology

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  • Contributors MK (corresponding author) had a contribution in drafting the manuscript, editing the manuscript, finalising the manuscript and liaising with other authors. He was also responsible for collating the images and submission to the journal. AD had a contribution in identifying the case, planning the manuscript and drafting the manuscript. MMK had a contribution in drafting the pathology section of the manuscript and analysing histology slides. JI had a contribution in drafting the manuscript, proofing the manuscript and finalising the manuscript.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.