Article Text

Download PDFPDF
A case of bronchiolitis obliterans organising pneumonia associated with SAPHO (synovitis-acne-pustulosis-hyperostosis-osteitis) syndrome
  1. Fawad Hameed1,
  2. Henry Steer2
  1. 1Department of Respiratory Medicine, Musgrove Park Hospital, Taunton and Somerset NHS Foundation Trust, Taunton, UK
  2. 2Department of Respiratory Medicine, Gloucestershire Royal Hospital, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK
  1. Correspondence to Dr Fawad Hameed, dr.fawad.hameed{at}


A 57-year-old woman with SAPHO (synovitis-acne-pustulosis-hyperostosis-osteitis) syndrome presented with recurrent episodes of pneumonia. She was treated with multiple courses of antibiotics with no success. The transbronchial biopsy undertaken via bronchoscopy revealed organising pneumonia (OP). She was treated with steroids and responded well with full clinical recovery and normalisation of her chest X-ray.

To our knowledge, this is the first reported case of OP in association with SAPHO syndrome. This case report highlights the importance of considering OP in patients with SAPHO syndrome who present with chest infection.

  • bronchiolitos
  • interstitial lung disease
  • pneumonia (respiratory medicine)
  • musculoskeletal syndromes
View Full Text

Statistics from


  • Contributors FH: collected the data and images, drafted the case report and literature search. HS: analysed the case report draft and literature search and advised necessary changes.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.