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A rare case of localised pigmented villonodular synovitis in the knee of a 24-year-old female soccer player: diagnosis, management and summary of tenosynovial giant cell tumours
  1. Casper Falster1,
  2. Simon Stockmann Poulsen2,
  3. Uffe Joergensen2
  1. 1Department of Molecular Endocrinology and Stem Cell Research Unit (KMEB), Odense University Hospital, Odense, Denmark
  2. 2Department of Orthopedic Surgery and Sports Traumatology, Odense University Hospital, Odense, Denmark
  1. Correspondence to and Casper Falster, cfalster{at}


Localised pigmented villonodular synovitis (PVNS) of the knee is a rare diagnosis, with clinical signs and symptoms mimicking meniscal damage or other common knee injuries.

We report the case of a 24-year-old female soccer player, seeking treatment after 7 months of persisting knee pain. Additionally, we present an overview of tenosynovial giant cell tumours.

On examination, the patient was found to have tenderness in the medial joint space of the knee. MRI revealed a heterogeneous formation in the central part of the knee. The formation was completely enucleated arthroscopically, histological analyses confirmed the diagnosis of localised PVNS. The patient was subsequently free of symptoms with no signs of recurrence on MRI and had resumed soccer practice at the 1-year follow-up appointment.

  • orthopaedics
  • orthopaedic and trauma surgery
  • pathology
  • radiology

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  • Contributors The authors declare that all authors have been equally involved in conceiving and writing this case report. As the primary author, CF has been in charge of contact with the patient in question; in addition, he has written the majority of the case report and has examined the literature in conjunction with second author, SSP. The last author, UJ, has provided support and guidance regarding literature search and scientific writing. All authors have approved the final version for publishing and agreed to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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