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Small cell lung cancer presenting as unilateral rhinorrhoea
  1. Adam Haymes1,
  2. Sridhayan Mahalingam2,
  3. Natasha Choudhury3
  1. 1Department of ENT, East Surrey Hospital, Redhill, Surrey, UK
  2. 2Department of ENT, Maidstone and Tunbridge Wells NHS Trust, Tunbridge Wells, Kent, UK
  3. 3Department of ENT, Surrey and Sussex Healthcare NHS Trust, Redhill, Surrey, UK
  1. Correspondence to Adam Haymes, haymesa{at}


The metastatic spread of infraclavicular malignancies to the nasal cavity is rare. We describe the case of a 58-year-old man who presented with a 4-month history of right-sided rhinorrhoea, maxillary hypoesthesia, hyposmia and hypogeusia. Clinical examination revealed an irregular mass within the right nasal cavity. Immunohistochemical analyses of biopsies were consistent with small cell carcinoma of indeterminate origin. A positron emission tomography scan demonstrated extensive mediastinal lymphadenopathy with collapse-consolidation of the right lung's middle lobe and no other sites of metastasis. Following discussion at the lung multidisciplinary team meeting, a diagnosis of metastatic small cell lung cancer (SCLC) was made; the patient was staged with N3, M1b disease and palliative chemo-radiotherapy was started. To the best of our knowledge, this report represents the first documented case of a solitary nasal cavity metastasis arising from a SCLC.

  • ear
  • nose and throat/otolaryngology
  • head and neck cancer
  • lung cancer (oncology)
  • head and neck surgery
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  • Contributors AH performed the literature search and drafted the case report. SM assisted in the drafting of the case report. ATH and SM performed revisions. NC was the consultant overseeing the patients care, reviewed revisions and gave final approval of the published version.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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