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Renal cell carcinoma with isolated breast metastasis
  1. Sarah M Dhannoon1,
  2. Ali A Alsaad2,
  3. Abdo R Asmar3,
  4. Fuad H Shahin4
  1. 1Department of Internal Medicine, University of Central Florida, Orlando, Florida, USA
  2. 2Department of Internal Medicine, Mayo Clinic Florida, Jacksonville, Florida, USA
  3. 3Department of Nephrology, University of Central Florida, Orlando, Florida, USA
  4. 4Department of General Surgery, Osceola Surgical Associate, Kissimmee, Florida, USA
  1. Correspondence to Dr Ali A Alsaad, alsaad.ali{at}, alsaad1984{at}


Renal cell carcinoma (RCC) is a highly prevalent disease worldwide with many cases being metastasised to various organs during the time of initial presentation. Metastatic RCC to the breast is a rare entity and can mimic primary breast carcinoma. In this article, we present a 63-year-old Caucasian woman presented with a breast mass that was detected by screening mammography and found to have a biopsy proven grade-II clear RCC in the breast tissue. Despite the high incidence and prevalence of primary breast cancer, metastasis from extramammary should be suspected in patients with a prior history of other cancers. In this brief literature review, we also highlight the survival benefit from surgery and close follow-up in selected group of patients with metastatic, metachronous and solitary RCC.

  • urological cancer
  • breast cancer
  • screening (oncology)

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  • Contributors SMD and AAA authored the manuscript and conducted the literature review. AAA reviewed and interpreted the images and designed the figures. ARA and FHS critically reviewed the manuscript. All authors approved the manuscript prior to submission.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.