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Bilateral interstitial keratitis with anterior stromal infiltrates associated with reactive arthritis
  1. Yi Eve Hsing,
  2. James Walker
  1. Caloundra Hospital, Caloundra, Australia
  1. Correspondence to Dr Yi Eve Hsing, hsingeve{at}


A previously healthy 48-year-old man presented with a 1-week history of migrating polyarthropathy preceded by a viral illness, dysuria and bilateral red eyes. Ocular examination revealed anterior and interstitial stromal keratitis. He was systemically well but had raised erythrocyte sedimentation rate and C reactive protein and was positive for human leucocyte antigen B27 on extensive infective, rheumatological and autoimmune investigations. Although the exact triggering pathogen was not identified, clinical findings were consistent with reactive arthritis. Bilateral interstitial keratitis is a rare manifestation of reactive arthritis which, along with the anterior stromal keratitis, responded well to topical prednisolone sodium phosphate 0.5%. Systemic joint symptoms improved on oral sulfasalazine, non-steroid anti-inflammatory agent and low-dose prednisolone.

  • ophthalmology
  • rheumatology
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  • Contributors JW and YEH were involved in the management of and capturing photographs of the patient. YEH prepared the manuscript. JW supervised the writing and editing of the report.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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