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Massive haemolysis, gas-forming liver abscess and sepsis due to Clostridium perfringens bacteraemia
  1. Rafael García Carretero1,
  2. Marta Romero Brugera2,
  3. Oscar Vazquez-Gomez3,
  4. Noelia Rebollo-Aparicio4
  1. 1Hospital Universitario de Mostoles, Mostoles, Madrid, Spain
  2. 2Department of Emergency, Hospital Universitario de Mostoles, Mostoles, Madrid, Spain
  3. 3Department of Infectious Diseases, Hospital Universitario de Mostoles, Mostoles, Madrid, Spain
  4. 4Department of Internal Medicine, Hospital Universitario de Mostoles, Mostoles, Madrid, Spain
  1. Correspondence to Dr Rafael García Carretero, rgcarretero{at}


Clostridial soft tissue infections are infrequent, but can be life-threatening when associated with certain underlying conditions, such as immunosuppression or malignancy. When bacteraemia occurs, it can be accompanied by haemolysis. Only surgical removal of the focus of infection and early onset of antibiotic therapy can prevent a very poor outcome. We describe the case of a man aged 65 years who presented with sepsis, haemolysis and rapid worsening. The identification of a gas-forming liver abscess, the early percutaneous drainage and the prompt initiation of antibiotic treatment were the key factors in the outcome of this patient.

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  • Twitter Follow Rafael García Carretero at @rafa_linux

  • Contributors RGC wrote the first draft; MRB and OV-G made interesting suggestions; NR-A helped in the translation into English.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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