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Rare case of T-cell lymphoma presenting as acute myelopathy
  1. Verena Clarissa Samara,
  2. Adam de Havenon
  1. Department of Neurology, University of Utah, Salt Lake City, Utah, USA
  1. Correspondence to Dr Verena Clarissa Samara, verena.samara{at}


Acute myelopathy is a rare presentation of systemic T-cell lymphoma. We present the case of a man aged 68 years with a diffuse erythematous maculopapular rash, followed by lower extremity paresthesias and progressive lower extremity weakness. Spinal MRI showed longitudinally extensive T2 hyperintensity with diffuse contrast enhancement. An atypical clonal T-lymphocyte population was identified in cerebrospinal fluid, peripheral blood and bone marrow aspirate, indicating a malignant T-cell lymphoproliferative disorder. The patient was treated with intrathecal and systemic chemotherapy. Unfortunately, he was not responsive to chemotherapy.

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  • Contributors VCS drafted the article. AdH edited the article.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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