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Advanced gastric cancer linitis plastica presented with disseminated intravascular coagulation
  1. Sehem Ghazala,
  2. Jawad Bilal,
  3. Irbaz Bin Riaz
  1. Department of Internal Medicine, University of Arizona, Tucson, Arizona, USA
  1. Correspondence to Dr Sehem Ghazala, sghazala{at}


An old man was found unconscious; on admission found to have disseminated intravascular coagulation with concern of upper gastrointestinal bleed after he was found to have melena. Esophagogastroduodenoscopy on admission showed diffuse thickened gastric folds, and biopsy showed mucosal oedema. Bone marrow biopsy concerning for lymphoma was obtained showed adenocarcinoma. MRI of the abdomen was significant for diffuse gastric wall thickening. A repeat endoscopic ultrasound showed a diffuse gastric wall thickening of 15 mm and submucosal tunneling technique biopsy suggested high-grade, invasive, signet ring adenocarcinoma of the stomach. Oncology was consulted to initiate palliative chemotherapy. In retrospect, the patient was questioned regarding gastrointestinal symptoms; he reported gradual early satiety, dysphagia and unintentional weight loss over the course of 4 months.

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  • Contributors SG wrote the introduction, summery, case presentation and contributed to the discussion. JB focused mainly on the discussion. IBR involved inpatient patient care and drafted the final version.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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