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Metastatic trichilemmal carcinoma in a patient with breast cancer
  1. Chrysis Sofianos,
  2. Nkhensani Y Chauke,
  3. Alexandra Grubnik
  1. Department of Plastic and Reconstructive Surgery, University of the Witwatersrand, Johannesburg, South Africa
  1. Correspondence to Dr Chrysis Sofianos, sofianosc{at}


Trichilemmal carcinoma (TC) is described as a very rare cancer of the skin adnexa.1 2 Ninety per cent of the lesions present on the scalp. Prognostic factors in TC are limited to lymph node status and surgical margins, with no statistical significance observed for age or gender of the patient, size of tumour or locoregional recurrence. We present a 46-year-old black patient who developed TC during treatment for breast cancer. Postoperative histology of the scalp lesion excision confirmed no involved margins. At the three monthly appointment, the patient was reviewed and multiple, new scalp lesions were noted. A CT scan of the head, neck found multiple lesions on the scalp, limited to the soft tissue, not involving the outer table of the skull. There was bilateral invasion of the parotid glands. To the best of our knowledge, no syndromes or associations between breast cancer and adnexal skin tumours exist.

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  • Twitter Follow Chrysis Sofianos at @sofianosc

  • Contributors CS was involved with the conception of the work; literature review; interpretation of the case report; drafting of the article; critical revision of the article. NYC was involved with the conception of the work; data collection; interpretation of the case report; critical revision of the article. AG was involved with the conception of the work; critical revision of the article. All authors of this article have made substantial contributions to the article. All authors gave final approval of the submitted manuscript.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.