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Smooth muscle tumour of uncertain malignant potential (SMTUMP) in the nasal cavity: an incidental finding
  1. Dipak Ranjan Nayak1,
  2. Asheesh Dora Ghanpur2,
  3. Apoorva N Reddy3,
  4. Swati Sharma4
  1. 1Department of Otolaryngology—Head and Neck Surgery, Kasturba Medical College, Manipal, Karnataka, India
  2. 2Department of ENT, Head and Neck Surgery, Kasturba Medical College, Manipal, Karnataka, India
  3. 3Department of Otorhinolaryngology—Head and Neck Surgery, Kasturba Medical College, Manipal, Karnataka, India
  4. 4Department of Pathology, Kasturba Medical College, Manipal, Karnataka, India
  1. Correspondence to Dr Dipak Ranjan Nayak, drnent{at}


Sino-nasal smooth muscle tumours of uncertain malignant potential (SMTUMP) are very rare neoplasms of mesenchymal origin with features in between a benign leiomyoma and a leiomyosarcoma. We report a rare case of SMTUMP in a 44-year-old woman, who presented with vague symptoms of pharyngitis. Nasal endoscopy revealed a smooth mass in left nasal cavity. Contrast-enhanced CT and MRI scans showed features likely to be inverted papilloma or olfactory neuroblastoma or meningioma. Excision was planned and intraoperatively, frozen section revealed a probable spindle cell lesion. Final histopathological report following immunohistochemistry (IHC) & immunofluoresence (IF) confirmed it to be a SMTUMP. This patient underwent complete resection via endoscopic KTP laser assisted, anterior skull base surgery with no recurrence on follow-up.

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  • Contributors DRN involved in diagnosis; is the operating surgeon; contemplated to report this case; contributed to intraoperative findings, steps of procedure performed and recording and editing of the surgery; obtained postoperative pictures and involved in drafting and proof reading of the paper. ADG involved in review of literature and contributed to drafting the paper, editing of pictures, documentation, formatting and proof reading of the paper. ANR involved in procuring the consent, assisted in the surgery and helped in drafting the operative findings and procuring the histopathology slides. SS obtained details of histopathology and immunohistochemistry. All authors were not only involved in the patient care but also have actively participated in drafting of the paper. All authors have personally procured the data regarding the case, have reviewed the literature and have given inputs for the case report.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.