Summary

A Caucasian man aged 28 years with a history of pancreatitis presented with fatigue, intermittent melaena and severe anaemia. Symptomatic treatment for anaemia was coupled with thorough investigation to localise the source of gastrointestinal haemorrhage. Two oesophagogastroduodenoscopies and colonoscopies failed to identify a cause. CT abdomen revealed splenomegaly secondary to splenic vein thrombosis with evidence of portal hypertension and small collateral vessels. A CT mesenteric angiogram revealed a splenic artery pseudoaneurysm as the likely source of bleeding. This was embolised successfully via interventional radiology and the patient's haemoglobin levels stabilised. During admission, the patient also developed severe epigastric pain radiating to the back secondary to acute-on-chronic pancreatitis, as evidenced by MRCP. The acute pancreatitis resolved with medical management, but the pain from his chronic condition was extremely difficult to control, even with opioids. He consequently underwent a successful splenic nerve radiofrequency ablation.