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Anaplastic large cell lymphoma masquerading as osteomyelitis of the shoulder: an uncommon presentation
  1. Matthew Tuck1,2,
  2. Jane Lim3,
  3. Jose Lucar4,
  4. Debra Benator2
  1. 1Department of Medicine, George Washington University, Washington, DC, USA
  2. 2Department of Medical Services (111), Veterans Affairs Medical Center, Washington, DC, USA
  3. 3Department of Internal Medicine, Cedars-Sinai Health System, Los Angeles, California, USA
  4. 4Division of Infectious Diseases, Department of Medicine, University of Mississippi Medical Center, Jackson, Mississippi, USA
  1. Correspondence to Dr Matthew Tuck, matthew.tuck{at}


The presentation of anaplastic lymphoma kinase protein (ALK)-negative anaplastic large cell lymphoma (ALCL) in bone is rare. We describe a patient with ALK-negative ALCL presenting with clinical and radiographic findings suggesting osteomyelitis 6 months after left rotator cuff repair surgery. A review of the characteristics of ALK-negative ALCL with primary bone involvement is presented. ALCL should be considered in patients not responding to therapies for osteomyelitis.

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  • Contributors All authors have made substantial contributions to the conception, drafting of this manuscript and critical revision. All authors gave final approval for the version being submitted. Specific contributions are as listed: MT, JL and DB contributed to literature review; MT and JL contributed to drafting of the manuscript.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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