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Importance of diagnostic work-up of Guillain-Barré syndrome in pregnancy
  1. Elza Pollak-Christian1,
  2. Kyong-Soon Lee2,3
  1. 1Department of Pediatrics, State University of New York Downstate Medical Center, Brooklyn, New York, USA
  2. 2Department of Neonatology, The Hospital for Sick Children, Toronto, Ontario, Canada
  3. 3University of Toronto, Toronto, Ontario, Canada
  1. Correspondence to Dr Elza Pollak-Christian, elzapollak{at}


We report a full-term neonate presenting with symptomatic congenital cytomegalovirus (CMV) infection with hepatosplenomegaly, ‘blueberry muffin’ rash, intracranial calcifications, thrombocytopenia and respiratory distress. Maternal history was relevant for Guillain-Barré syndrome (GBS) during the first trimester of pregnancy. CMV infection is an important cause of GBS; thus, women presenting GBS during pregnancy should be screened for CMV infection. If positive, they may benefit from specialised monitoring and treatment in the antenatal period, which may decrease the risk of major neurodevelopmental sequelae of congenital CMV in the neonate.

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  • Contributors EP-C was involved in the drafting of the manuscript and associated editing. K-SL was involved in the care and follow-up of the patient. K-SL was additionally involved in manuscript revision and approval of the manuscript to be published. K-SL was directly involved in all editing of the manuscript.

  • Competing interests None declared.

  • Patient consent Obtained.

  • Provenance and peer review Not commissioned; externally peer reviewed.