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‘Inflammatory breast cancer’ due to metastatic adenocarcinoma of lung
  1. Jacob Ninan1,
  2. Vinay Naik2,
  3. Gemy Maria George3
  1. 1Mayo Clinic Health Systems—Franciscan Healthcare, Department of Hospital Medicine, La Crosse, Wisconsin, USA
  2. 2Department of Pathology, Mayo Clinic Health Systems—Franciscan Healthcare, La Crosse, Wisconsin, USA
  3. 3Department of Internal Medicine, John H Stroger Jr. Hospital of Cook County, Chicago, Illinois, USA
  1. Correspondence to Dr Jacob Ninan, ninan.jacob{at}


A 67-year-old woman with a history of lung adenocarcinoma presented with 3 weeks of redness, pain, swelling and skin changes in her right breast. Her vital signs and physical examination were within physiological limits except for the right breast. She had extensive red streaks radiating from the right nipple with peau d'orange appearance of her overlying skin. Her breast was tender on examination and did not have any associated cervical or axillary lymphadenopathy. Her mammography revealed thickening of the skin, increased parenchymal markings and shrinkage the breast. Multiple skin biopsies demonstrated moderately differentiated lung adenocarcinoma with lymphovascular invasion. The patient made an informed decision to undergo radiotherapy following discussion with her oncologist and breast surgeon. She succumbed to her illness 2 months after the diagnosis of metastasis to her breast.

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