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An 85-year-old man with type 2 diabetes mellitus presented to our emergency department with sudden right limb weakness and dysarthria 90 min after onset. He was alert when examined and had a blood pressure of 163/89 mm Hg. Although right hemiplegia with facial weakness and dysarthria were noted, sensations to pinpricks were intact. MRI showed a hyperintense lesion in the posterior limb of the left internal capsule (IC), with decreased apparent diffusion coefficient values on diffusion-weighted imaging (DWI), suggesting acute ischaemic stroke (AIS) (figure 1). In the coronal plane, the lesion appeared along the pyramidal tract, suggesting a pathology other than AIS. A laboratory examination revealed a decrease in the serum glucose level (32 mg/dL), whereon 40 mL of a 50% glucose solution was infused. The patient made a complete recovery without neurological deficits; follow-up MRI 2 days later revealed complete lesion resolution (figure 2). Based on the clinical course, hypoglycaemic hemiplegia was diagnosed. Hypoglycaemia may present with focal neurological signs such as hemiplegia.1 Moreover, hypoglycaemic hemiplegia can result in hyperintense lesions in the IC being noted on DWI, which are difficult to distinguish from AIS.2 However, although AIS lesions may be detected along the vascular territory, hypoglycaemic hemiplegia lesions might be present along the pyramidal tract, since the more compact neuronal tissue might be more vulnerable to hypoglycaemia.3 The coronal section in this case shows that the lesion is actually along the pyramidal tract and, to prevent a misdiagnosis, the coronal section is therefore very useful.
Hypoglycaemic hemiplegia may mimic acute ischaemic stroke, not only clinically, but also radiologically.
Hypoglycaemic hemiplegia should be considered in cases where diffusion-weighted imaging shows hyperintense lesions along the pyramidal tract in the coronal plane.
A coronal section may be useful in distinguishing hypoglycaemic hemiplegia from acute ischaemic stroke.
Contributors KT was responsible for study concept and design, drafting and revising the manuscript, analysis and interpretation of data. TK was responsible for drafting the article and revising it critically for important intellectual content. TS was responsible for study concept and design, drafting and revising the manuscript, analysis and interpretation of data, and is guarantor of the study.
Competing interests None declared.
Patient consent Obtained.
Provenance and peer review Not commissioned; externally peer reviewed.
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