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Pseudomembranous colitis secondary to methicillin-resistant Staphylococcus aureus (MRSA)
  1. Kalynn B Pressly,
  2. Emilie Hill,
  3. Kairav J Shah
  1. Department of Medicine, Division of Infectious Diseases, University of Florida, Gainesville, Florida, USA
  1. Correspondence to Dr Kairav J Shah, kairav.shah{at}


A 37-year-old woman with a history of type II diabetes and Crohn's disease, status postcholecystectomy, presented with a >2-week history of cramping abdominal pain, nausea, non-bloody/non-bilious emesis and, later, diarrhoea. A flexible sigmoidoscopy was performed, revealing that ‘a segmental pseudomembrane was found from rectum to sigmoid colon’. Clostridium difficile PCR on the stool was repeated twice and resulted negative both times. A food history prior to onset of symptoms was consistent with Staphylococcal food poisoning and a stool culture was positive for heavy growth of methicillin-resistant Staphylococcus aureus and the absence of enteric flora. The patient was successfully treated with oral vancomycin.

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