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CASE REPORT
An unusual response with long term survival using erlotinib in NSCLC lung with brain metastases
  1. Madhup Rastogi1,
  2. Sambit Swarup Nanda1,
  3. Chandra Prakash1,
  4. Dinkar Kulshreshtha2
  1. 1Department of Radiation Oncology, Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
  2. 2Department of Neurology, Ram Manohar Lohia Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
  1. Correspondence to Dr Madhup Rastogi, drmadhup1{at}rediffmail.com

Summary

We present a case of a middle-aged woman with adenocarcinoma of the lung and metastatic brain lesions. In view of her poor general condition and poor compliance to first-line chemotherapy, the patient was kept on tablet erlotinib after whole brain radiotherapy. This novel treatment resulted in a dramatic response with radiological regression in both the primary lung lesion and metastatic intracranial lesions translating in unexpected and ongoing 24-month survival.

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