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Cervical spinal cord compression complicating the clinical course of Charcot-Marie-Tooth type 1
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  1. Matthew R B Evans1,
  2. Matilde Laurá1,
  3. Hoskote Chandrashekar2,
  4. Mary M Reilly1
  1. 1MRC Centre for Neuromuscular Diseases, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK
  2. 2Academic Neuroradiological Unit, UCL Institute of Neurology and National Hospital for Neurology and Neurosurgery, London, UK
  1. Correspondence to Dr Matthew RB Evans, matthew.evans{at}ucl.ac.uk

https://doi.org/10.1136/bcr-2015-213486

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    Description

    A 73-year-old woman with Charcot-Marie-Tooth type 1 (CMT1) had followed a typical slowly progressive course since onset. She had bilateral distal upper and lower limb weakness and walked with a single stick from 50 years of age, requiring two sticks following a left internal capsular stroke at 63 years of age. Neurological examination was consistent with a severe, length-dependent sensorimotor neuropathy: distal wasting/weakness in all limbs, with additional mild right lower limb pyramidal pattern weakness consistent with the previous stroke. There was decreased vibration …

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