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CASE REPORT
Tamoxifen-associated portal vein thrombosis causing severe oesophageal variceal bleeding
  1. Andrew Hsu1,
  2. Edward Belkin2,
  3. Samuel Han1,
  4. Randall Pellish2
  1. 1Department of Medicine, University of Massachusetts, Worcester, Massachusetts, USA
  2. 2Department of Gastroenterology, University of Massachusetts, Worcester, Massachusetts, USA
  1. Correspondence to Dr Andrew Hsu, andrew.hsu{at}umassmemorial.org

Summary

A 46-year-old woman with medical history of breast cancer on tamoxifen presented with syncope. On arrival to the hospital, the patient developed massive haematemesis and a subsequent esophagogastroduodenoscopy revealed oesophageal varices without any known history of liver disease. Further evaluation identified portal vein thrombosis probably caused by tamoxifen use.

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