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Bony non-union in a patient receiving androgen deprivation therapy for prostate cancer
  1. Adeel Ikram1,
  2. Jagwant Singh2,
  3. Ahmad Ali3
  1. 1Peripheral Nerve Injury Unit, Royal National Orthopaedic Hospital, London, Middlesex, UK
  2. 2Colchester Hospital University NHS Foundation Trust, Colchester, UK
  3. 3Department of Trauma and Orthopaedics, Queens Hospital, London, UK
  1. Correspondence to Dr Adeel Ikram, adeelikram{at}


We present a case of a 76-year-old man who underwent a corrective femoral osteotomy for a varus deformity and stress fractures. The patient was on androgen deprivation therapy (ADT) for prostate cancer and the osteotomy failed to heal. At 13 months, the ADT was stopped and bony union was achieved in 3 months. Orthopaedic surgeons treating fractures in this patient population need to aware of the problems associated with ADT and closely liaise with oncologists and urologists to stop ADT or start alternative treatment until bony union has been achieved.

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