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Unprovoked deep venous thrombosis in a young adult associated with membranous obstruction of inferior vena cava
  1. Narendranath Epperla1,
  2. Natalia Usoltseva2
  1. 1Department of Hematology and Oncology, Medical College of Wisconsin, Milwaukee, Wisconsin, USA
  2. 2Department of Internal Medicine, Cascade Skagit Health Alliance, Mount Vernon, Washington, USA
  1. Correspondence to Dr Narendranath Epperla, nepperla{at}


Unprovoked deep venous thrombosis (DVT) in young adults is an unusual phenomenon, but it is associated with significant morbidity. Developmental anomalies of the inferior vena cava (IVC) should be considered as a possible aetiological factor, and appropriate investigations should be performed to determine the conclusive diagnosis and necessary treatment plan. We report a case of spontaneous thrombosis of the IVC and bilateral iliac venous system in a young man, associated with membranous obstruction of the IVC. He was diagnosed using several different investigational techniques, and successfully treated with mechanical thrombectomy, thrombolysis therapy and anticoagulation.

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