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Diffuse large B-cell lymphoma of the cauda equina
  1. Martijn Broen1,
  2. Tim Draak1,
  3. Robert G Riedl2,
  4. Wim E J Weber1
  1. 1Department of Neurology, MUMC, Maastricht, The Netherlands
  2. 2Department of Pathology, Maastricht University Medical Center, Maastricht, The Netherlands
  1. Correspondence to Dr Wim E J Weber,{at}


Primary central nervous system (CNS) lymphoma is a rare form of non-Hodgkin's lymphoma. The clinical presentation is variable, depending on its localisation within the nervous system. Only 1% of primary CNS lymphoma emerges in the spinal cord, and the prevalence of primary lymphoma of the cauda equina is unknown, but probably even rarer. Diagnosing primary lymphoma of the cauda equina is difficult, since it can mimic other more common disorders such as a herniated disc, especially in its early stages. Here we present two cases of primary cauda equina lymphoma in which diagnostic work up took a long time, as the final diagnosis was only reached after a nerve root biopsy.

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