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Panhypopituitarism secondary to a solitary hypothalamic metastasis
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  1. Mark Ellul1,
  2. Tobias Janowitz1,
  3. Neil Burnet2
  1. 1Department of Oncology, Addenbrooke's Hospital, Cambridge, UK
  2. 2Department of Oncology, University of Cambridge, Cambridge, UK
  1. Correspondence to Dr Mark Ellul, markalexellul{at}gmail.com

https://doi.org/10.1136/bcr-2014-204283

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    A 50-year-old woman with breast cancer and widespread skeletal metastases presented with lethargy, weight gain and memory loss. Blood tests showed panhypopituitarism: thyroid-stimulating hormone 0.17 mU/L (0.35–5.5), free T4 4.2 pmol/L (10–19.8), free T3 1.2 pmol/L (3.5–6.5), luteinising hormone <0.1 µmol/L (16–75 postmenopausal), follicle-stimulating hormone <0.3 U/L (21–140 postmenopausal) and random cortisol 32 nmol/L. Prolactin was also low …

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