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Primary colonic signet ring cell carcinoma in a young patient
  1. Raghunath Prabhu1,
  2. Neha Kumar2,
  3. Sunil Krishna3,
  4. Rajgopal Shenoy3
  1. 1Department of Surgery, Kasturba Medical College, Manipal, Karnataka, India
  2. 2UHNS, Warwickshire, UK
  3. 3Department of General Surgery, Kasturba Medical College, Manipal, Karnataka, India
  1. Correspondence to Dr Raghunath Prabhu, drraghu81{at}


A 28-year-old woman presented with colicky abdominal pain for 3 months. Pain was associated with episodes of vomiting, abdominal distension and constipation. She also had loss of weight for this duration. General physical examination was unremarkable and the abdomen was soft, with no palpable organomegaly. A CT of the abdomen showed small bowel and ascending colon dilation with multiple air fluid levels. There was also a short segment of circumferential bowel wall thickening and luminal narrowing in the hepatic flexure with sudden transition of bowel diameter. She underwent a right hemicolectomy after necessary preoperative investigations. Histopathology revealed signet ring cell carcinoma (SRCC). This case highlights the importance of detecting such a lesion in a young, otherwise fit woman. The challenge lies in early diagnosis and awareness of general practitioners about this aggressive form of colonic tumours.

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