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Postural orthostatic tachycardia syndrome (POTS)
  1. Bharat Sidhu1,
  2. Nonyelum Obiechina2,
  3. Noman Rattu2,
  4. Shanta Mitra3
  1. 1Department of General Medicine, NHS, Birmingham, West Midlands, UK
  2. 2Department of Elderly Care & General Medicine, Queens Hospital Burton, Birmingham, UK
  3. 3Department of General Medicine, Queens Hospital Burton, Birmingham, UK
  1. Correspondence to Dr Bharat Sidhu, b.sidhu2{at}


Postural orthostatic tachycardia syndrome (POTS) is a heterogeneous group of conditions characterised by autonomic dysfunction and an exaggerated sympathetic response to assuming an upright position. Up till recently, it was largely under-recognised as a clinical entity. There is now consensus about the definition of POTS as a greater than 30/min heart rate increase on standing from a supine position (greater than 40/min increase in 12–19-year-old patients) or an absolute heart rate of greater than 120/min within 10 min of standing from a supine position and in the absence of hypotension, arrhythmias, sympathomimetic drugs or other conditions that cause tachycardia. We present two cases of POTS, followed by a discussion of its pathogenesis, pathophysiology, epidemiology and management.

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