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CASE REPORT
Splenectomy complicated by sustained extreme thrombocytosis and extensive portosplenomesenteric vein thrombosis in pyrimidine 5′-nucleotidase deficiency
  1. Hassan A Al-Jafar1,
  2. Ali Taqi2,
  3. John Patrick Madda3,
  4. Thamer A Abdullah4
  1. 1Department of Haematology, Amiri Hospital, Kuwait City, Kuwait
  2. 2Department of Surgery, Amiri Hospital, Kuwait City, Kuwait
  3. 3Department of Histopathology, Amiri Hospital, Kuwait City, Kuwait
  4. 4Department of Radiology, Amiri Hospital, Kuwait City, Kuwait
  1. Correspondence to Dr Hassan A Al-Jafar, cbc9{at}hotmail.com

Summary

Reactive and redistributional thrombocytosis is a well-known postsplenectomy occurrence .Usually it is transient and it rarely reaches extreme levels. We report a rare case of haemolytic anaemia where splenectomy was carried out following trauma to a massively enlarged spleen and was followed by extreme sustained thrombocytosis associated with extensive portal, splenic and mesenteric vein thrombosis despite standard antithrombotic prophylaxis.

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