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CASE REPORT
Intravitreal bevacizumab as an adjunct in the management of a vascular choroidal granuloma
  1. Reema Bansal1,
  2. Nikhil Beke1,
  3. Aman Sharma2,
  4. Amod Gupta3
  1. 1Advanced Eye Centre, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  2. 2Department of Internal Medicine, Post Graduate Institute of Medical Education and Research, Chandigarh, India
  3. 3Department of Ophthalmology, Post Graduate Institution of Medical Education and Research, Chandigarh, India
  1. Correspondence to Dr Amod Gupta, eyepgi{at}sify.com

Summary

A 43-year-old woman with tubercular choroidal granuloma showed poor response to conventional first-line four-drug antitubercular therapy (ATT) and corticosteroids. A therapeutic trial with intravitreal bevacizumab (1.25 mg in 0.05 mL) injections as an adjunct to ATT and corticosteroids led to a prompt initial regression of granuloma with restoration of visual acuity that was sustained for almost 2 years. A subsequent recurrence of the same lesion with evidence of enhanced vascularity was treated with intravitreal bevacizumab alone, that led to a complete regression of the granuloma with no recurrence until 1 year of follow-up.

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