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Gelatinous bone marrow transformation secondary to unusual eating habits and drastic weight loss
  1. Rafiullah1,
  2. Rezwan Islam2,
  3. Ruth Mahmood1,
  4. Kajal V Sitwala3
  1. 1Department of Internal Medicine, Ministry Saint Clare's Hospital, Weston, Wisconsin, USA
  2. 2Department of Oncology/Hematology, Marshfield Clinic, Weston, Wisconsin, USA
  3. 3Department of Laboratory Medicine, Marshfield Clinic, Marshfield, Wisconsin, USA
  1. Correspondence to Dr Rafiullah, drrafiullahkhan{at}


Gelatinous bone marrow transformation (GMT), also known as starvation bone marrow, has been reported in a number of chronic illnesses, eating disorders (anorexia nervosa) and malignancies. We report the case of a 37-year-old man with a history of bipolar disorder and obesity (weighing >300 pounds) who presented due to recently developing a deep yellow colour to his skin. Over the past 2 years, through diet and exercise, he lost over 150 pounds. He reported running 6–8 miles per day and eating ‘lots of squash’. We made the diagnosis of starvation hepatitis and bone marrow degeneration, and referred the patient to a dietician and haematologist/oncologist, where improvements were observed at 4 weeks follow-up.

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