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Multilocular cystic renal cell carcinoma: a rare entity
  1. Atin Singhai1,
  2. Suresh Babu1,
  3. Nidhi Verma1,
  4. Vishwajeet Singh2
  1. 1Department of Pathology, King George's Medical University, Lucknow, Uttar Pradesh, India
  2. 2Department of Urology, King George's Medical University, Lucknow, Uttar Pradesh, India
  1. Correspondence to Dr Atin Singhai, atinsinghai{at}

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Multilocular cystic renal cell carcinoma (MCRCC) is an uncommon subtype of clear cell renal cell carcinoma that appears to have a favourable prognosis. Literature reports a very low incidence of 1–2% of MCRCC among the renal neoplasms. The first such reported case was in 1957 by Robinson. In 1998, Eble et al suggested following diagnostic criterion for MCRCC: (1) an expansile mass surrounded by a fibrous capsule; (2) interior of tumour entirely composed of cysts and septa with no expansile nodule or solid component confined to more than 10% of entire tumour and (3) septa containing aggregates of clear epithelial cells. We report a case of MCRCC in a 60-year-old male patient who presented with abdominal lump and after suspicion of renal malignancy underwent nephrectomy. The patient was perfectly well till last follow-up of 3 months postoperatively.


Multilocular cystic renal cell carcinoma (MCRCC) is a rare entity of renal neoplasms and has been recently added to the WHO classification of renal neoplasms.1–4 Because of its close resemblance to other cystic renal lesions, it tends to get missed. This manuscript has been written to provide clear-cut distinction between the cystic renal neoplasms, by citing this case, as otherwise MCRCC has an excellent prognosis and often does not show recurrence or …

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