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The use of ozone therapy in Buruli ulcer had an excellent outcome
  1. Antonella Bertolotti1,
  2. Annunziata Izzo1,
  3. Pier Giovanni Grigolato2,
  4. Maria Letizia Iabichella1
  1. 1InterMed Onlus, Brescia, Italy
  2. 2Department of Pathology,  University Brescia, Brescia, Italy
  1. Correspondence to Dr Maria Letizia Iabichella, ml.iabichella{at}


This is the first case reporting the effective use of 2 weeks of ozone therapy for the treatment of Buruli ulcer (BU), a dramatic disease caused by Mycobacterium ulcerans, an epidemic in central Africa. This simple and cheap treatment could become an effective option for managing BU as an alternative to antibiotic or surgical treatments.

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