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Severe rhabdomyolysis associated with a primary cytomegalovirus infection in an immunocompetent patient
  1. Héloïse Gindre1,
  2. Léonard Féasson2,
  3. Christian Auboyer3,
  4. Pascal Cathébras1
  1. 1Department of Internal Medicine, CHU de Saint-Etienne, Saint-Etienne, France
  2. 2Department of Neurology, CHU de Saint-Etienne, Saint-Etienne, France
  3. 3Department of Intensive Care, CHU de Saint-Etienne, Saint-Etienne, France
  1. Correspondence to Professor Pascal Cathébras, pascal.cathebras{at}


Virus-induced rhabdomyolysis rarely induces respiratory failure. We discuss here a case of severe rhabdomyolysis with acute respiratory failure secondary to a cytomegalovirus (CMV) primary infection. We report a case of severe acute rhabdomyolysis, leading to respiratory failure and mechanical ventilation, associated with CMV primary infection in a young and otherwise healthy woman. We excluded other aetiologies such as metabolic myopathies, electrolyte disorders or Guillain-Barré syndrome with exhaustive researches. After 1 year, the patient recovered completely, apart from a slight muscle deconditioning. In this report, we compare our patient with five other similar cases found in the literature; our patient had the most severe presentation. The mechanism of acute viral-induced rhabdomyolysis remains elusive.

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