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CASE REPORT
Anaphylaxis to ibuprofen in a 12-year-old boy
  1. Emily Kay1,
  2. Moshe Ben-Shoshan2
  1. 1Department of Paediatrics, Montreal Children's Hospital, McGill University Health Center, Montreal, Quebec, Canada
  2. 2Division of Paediatric Allergy and Clinical Immunology, Department of Paediatrics, Montreal Children's Hospital, McGill University Health Center, Montreal, Quebec, Canada
  1. Correspondence to Dr Moshe-Ben Shoshan, moshebenshoshan{at}gmail.com

Summary

Non-steroidal anti-inflammatory (NSAIDs) drugs are a group of medications acting through cyclooxygenase  (COX-1) and cyclooxygenase  (COX-2) enzymes inhibition. Hypersensitivity reactions to NSAIDs, although not rare, are poorly characterised and often go undiagnosed especially in children. We present in this paper a case of ibuprofen anaphylaxis that exemplifies the challenges involved in diagnosis and management of hypersensitivity reactions to NSAIDs.

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