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Rare disease
Clinically malignant atypical glomus tumour
  1. Fariba Binesh1,
  2. Ali Akhavan2,
  3. Shokouh Taghipour Zahir1,
  4. Taghi Roshan Bovanlu3
  1. 1Department of Pathology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  2. 2Department of Radiation Therapy, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  3. 3Department of Radiology, Shahid Sadoughi University of Medical Sciences, Yazd, Iran
  1. Correspondence to Dr Fariba Binesh, binesh44{at}


Glomus tumours (GTs) resemble the normal glomus body and have a predilection for skin and subcutaneous tissue. Although the majority of glomus tumours are small, benign neoplasms that occur in the dermis or subcutis of the extremities and cases of atypical or malignant variants have been reported. We report a case of a man who presented with a 1-year history of subcutaneous nodule in the right scapular area which was mildly tender. The nodule measured 2 cm. Microscopic examination showed features of glomus tumour with increased mitotic activity. These features, by current definition, would suggest glomus tumour of uncertain malignant potential. Three months later, he presented with recurrence. During his metastasis work-up, we noticed bilateral pulmonary metastasis. Metastasising GTs are rare. The patient underwent wide local excision and received chemotherapy.

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