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Unusual association of diseases/symptoms
Gingival pain: an unusual side effect of ziprasidone
  1. Ashwati Raghunath
  1. Sunnybrook Health Sciences Centre, Toronto, Ontario, Canada
  1. Correspondence to Dr Ashwati Raghunath, ashwati.r{at}


The patient is a 52-year-old man with schizophrenia who developed severe, unremitting gingival pain after his ziprasidone dosage was increased from 80 to 120 mg. His physical examination and laboratory findings were unremarkable. He did not have any extra-pyramidal side effects. His pain did not ameliorate after taking acetaminophen and non-steroidal anti-inflammatory drugs. As a last resort, the patient took benztropine and his pain subsided within half an hour. His ziprasidone dosage was decreased and the patient is currently doing well. He has not experienced gingival pain since his medication was adjusted.

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