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Acral erosive mycosis fungoides: successful treatment with localised radiotherapy
  1. Connie Mengyan Wang1,
  2. Madeleine Duvic2,
  3. Bouthaina Shbib Dabaja3
  1. 1Dermatology Department, Baylor College of Medicine, Houston, Texas, USA
  2. 2Department of Dermatology, UT AM Anderson Cancer Center, Houston, Texas, USA
  3. 3Department of Radiation Oncology, UT MD Anderson Cancer Center, Houston, Texas, USA
  1. Correspondence to Dr Bouthaina Shbib Dabaja, bdabaja{at}


Mycosis fungoides encompasses a wide range of variants with differing clinical and histopathological findings, clinical courses and methods of treatment. Two patients were referred to MD Anderson Cancer Center for the evaluation of treatment-refractory palmoplantar dermatoses suggestive of a rare variant of mycosis fungoides—mycosis fungoides palmaris et plantaris (MFPP). Both patients eventually had progressive and ulcerative cutaneous disease extending beyond acral regions that showed remarkable response to local radiation therapy. Although most documented cases of MFPP show an indolent course, one must be aware of the possibility of development of severe cutaneous disease in patients initially presenting with palmoplantar involvement. Local radiotherapy is a safe and effective palliative treatment option for MFPP and cutaneous disease refractory to systemic treatment.

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