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Rare disease
Triple negative mixed metaplastic breast carcinoma with squamous and spindle cells in an 84-year-old woman: a rare entity with unclear management strategy and poor prognosis
  1. Srujitha Murukutla1,
  2. Vijaya Raj Bhatt1,
  3. Abhirami Vivekanandarajah2,
  4. Cynara Coomer3,
  5. Shilpi Gupta2
  1. 1Department Of Medicine, Staten Island University Hospital, Staten Island, New York, USA
  2. 2Division Of Hematology/Oncology, Department of Medicine, Staten Island University Hospital, Staten Island, New York, USA
  3. 3Division of Breast Surgery, Department of Surgery, Staten Island University Hospital, Staten Island, New York, USA
  1. Correspondence to Dr Srujitha Murukutla, srujitha.murukutla{at}gmail.com

Summary

Metaplastic carcinoma of the breast, a rare neoplasm, usually presents at an advanced stage, metastasises to distant sites more frequently, has higher Ki-67 expression and is more often triple negative compared with other invasive breast cancers. Here, the authors discuss a case of an 84-year-old woman with triple negative mixed metaplastic breast carcinoma treated with radical modified mastectomy, axillary lymph node dissection and radiation therapy. Because of the rarity of the disease, the pathogenesis and the management remain controversial, thus contributing to overall poor prognosis.

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Footnotes

  • Competing interests None.

  • Patient consent Obtained.

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