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Rare disease
Severe hypernatremic dehydration associated with cerebral venous and aortic thrombosis in the neonatal period
  1. Mohammed Hbibi1,
  2. Sana Abourazzak2,
  3. Abdeladim Babakhouya1,3,
  4. Meryem Boubou4,
  5. Samir Atmani2,
  6. Siham Tizniti4,
  7. Abdelhak Bouharrou1,3
  1. 1Neonatal Intensive Care Unit, Hassan II University Hospital, Fez, Morocco
  2. 2Pediatrics Department, Hassan II University Hospital, Fez, Morocco
  3. 3Neonatology Department, Hassan II University Hospital, Fez, Morocco
  4. 4Radiology Department, Hassan II University Hospital, Fez, Morocco
  1. Correspondence to Dr Sana Abourazzak, abourazzak77{at}


Severe neonatal hypernatremia is an important electrolyte disorder that has serious effects. Cerebral venous thrombosis and aortic thrombosis are relatively rare in severe neonatal hypernatremic dehydration. The authors report a case of cerebral venous thrombosis, associated with aortic thrombosis revealed by dehydration in a 9-day-old boy. Diagnostic was performed using Doppler ultrasound and imaging techniques. Thrombosis was resolved after anticoagulation treatment with low-molecular weight heparin for 1 month, and then was substituted by oral anticoagulant. The case report is followed by a review of the literature dealing with clinical, aetiological and therapeutic aspects of neonatal thrombosis.

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  • Competing interests None.

  • Patient consent Obtained.

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